"C.B.11": A New Analgesic Drug

Faecal Blood Loss during Treatment with Ibufenac, a New Analgesic Drug.

Aspirin is a drug of great value, especially in the treatment of chronic rheumatic conditions, but many studies have shown that there is an association between the ingestion of aspirin and gastro-intestinal haemorrhage (Muir and Cossar, 1955; Lange, 1957; Alvarez and Summerskill, 1958; Stubbe, 1958). Using 51Chromium to measure faecal blood loss, Scott, Porter, Lewis, and Dixon (1961) found tha...

Advanced Analgesic Drug Delivery and Nanobiotechnology

Transdermal administration of analgesic medications offers several benefits over alternative routes of administration, including a decreased systemic drug load with fewer side effects, and avoidance of drug degradation by the gastrointestinal tract. Transdermal administration also offers a convenient mode of drug administration over an extended period of time, particularly desirable in pain med...

Au Nanoparticle Loaded with 6-Thioguanine Anticancer Drug as a New Strategy for Drug Delivery

In this study we suggested a new strategy for drug delivery of 6-thioguanine (6-TG) as a cancer drug by loading of this thiolic drug at a surface of Au nanoparticles. For this goal, we synthesized Au nanoparticle (Au/NPs) by reduction of tetrachloroauric (III) acid solutions by sodium borohydride and characterized Au/NPs by X-ray powder diffraction (XRD), dynamic light scattering (DLS), Ultravi...

Paracetamol and Ibuprofen - Analgesic Drug Prescription Patterns on Five International Paediatric Wards Analgesic Drug Use in Hospitalised Children

PDLA a potential new potent topical analgesic: a case report

Polymer D-lactic acid (PDLA) is a hydrogel that has been shown to sequester L-lactate (lactate). This reaction is rapid, spontaneous, and non-enzymatic. Lactate has been shown to have many functions within the nervous system including its use as a secondary fuel to sustain neural activity and as a neuromodulator. In the central nervous system, lactate is produced in glial cells and shuttled to ...